A new review published in JAMA Psychiatry suggests that the ketogenic (keto) diet may help reduce symptoms of depression, especially when people reach a true state of ketosis, follow stricter carb limits, or are not obese.
Researchers reviewed 50 studies with over 41,000 adults and found that those on very low-carb diets (10% or less of calories from carbs) showed the biggest improvements in depression symptoms. The diet didnât seem to affect anxiety.
Experts say these results support the idea that mental health and metabolism are closely linked. While the findings are promising, doctors caution that the keto diet should be used alongside standard treatments, not as a replacement, and only under medical supervision, since it can be hard to maintain and may have side effects like fatigue, nausea, or constipation.
Overall, the study highlights growing evidence that supporting brain health through metabolic approaches could become an important part of treating depression.
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